NOLVADEX (TAMOXIFENE CITRATE) PROFILE

Nolvadex Info

Nolvadex, a trade name for the drug tamoxifen citrate, is a non-steroidal agent that demonstrates potent anti-estrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not our strongest available remedy. We now have the drugs Arimidex, Femara, and Aromasin available to us, which notably prevents estrogen from being manufactured in the first place. Altering the effect of estrogen in the female body can cause a level of discomfort, so antiestrogens are most bearable when used after the point of menopause. Since Nolvadex is milder in comparison, it is more widely applicable and usually the first treatment option.

• This drug also shows the ability to increase production of FSH (follicle stimulating hormone) and LH (luteinizing hormone) in the male body.
• When an aromatase blocker is used, Arimidex is the best choice by far.
• Nolvadex is certainly the most popular anti-estrogen used by athletes today, no doubt because it is simply an effective product.

Nolvadex Side effects

No ance problems, no water retention, rarely high blood pressure. Nolvadex is liver toxic.

Effective dosage : 10-30 mg/day

A typical daily dosage for men is in the range of 10 to 30mg, the chosen amount obviously dependent on the level of effect desired. It is advisable to begin with a low dosage and work up, so as to avoid taking an unnecessary amount. The time in which Nolvadex is started also relies on individual needs of the user. If an athlete with a known sensitivity to estrogen is starting a strong steroid cycle, Nolvadex should probably be added soon after the cycle had been initiated. If estrogen is probably not going to be a major problem during the cycle (but will likely be after), Nolvadex is administered around the time exogenous steroid levels will drop. It will be continued for some weeks after, until the point when natural testosterone is thought to be at an acceptable level. As mentioned Hcg is often used at this point as well (see related profile for more detail). Women have also utilized Nolvadex in an effort to reduce the effect of their own endogenous estrogens. This can lower body fat concentrations, especially in stubborn areas like the hips and thighs. This is of course risky, as manipulating the effect of estrogen can become uncomfortable in women. Side effects like hot flashes, menstrual irregularities and a variety of complications with the reproductive system are all possible.